Comment on “High-Sensitivity C-Reactive Protein: Product Claims and the Food and Drug Administration”

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High-sensitivity C-reactive protein: product claims and the Food and Drug Administration.

To the Editor: Several articles in recent issues of Clinical Chemistry have made reference to the Dade Behring N High Sensitivity CRP (hs-CRP) assay and have indicated that it has been approved by the Food and Drug Administration (FDA) for cardiovascular risk prediction (1–3). Although the use of hs-CRP assays in the assessment of cardiovascular risk is clearly gaining momentum, the FDA-cleared...

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Counterpoint: Food and Drug Administration guidance for C-reactive protein assays: matching claims with performance data.

LM, et al. CDC/AHA workshop on markers of inflammation and cardiovascular disease: application to clinical and public health practice: report from the laboratory science discussion group. Circulation 2004;110:e545–9. 4. Ridker PM, Wilson PW, Grundy SM. Should C-reactive protein be added to metabolic syndrome and to assessment of global cardiovascular risk? Circulation 2004;109:2818–25. 5. US Fo...

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The Effect of Resistance Training on Levels of Interlukine-6 and High-Sensitivity C - reactive protein in Older-Aged Women

Introduction: Aging is associated with elevated levels of some proinflammatory factors and exercise is a non-invasive intervention to improve immune function among older adults .The aim of the study was to compare resistance training effects on interlukine-6 (IL-6) and high-sensitivity C-reactive protein (hs-CRP) levels in older-aged women. Methods: The study was quasi-experimental and for...

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High-Sensitivity C-Reactive Protein and Cancer

BACKGROUND High-sensitivity C-reactive protein (hs-CRP) is a commonly used inflammatory marker. The association between hs-CRP and cancer is less consistent than that between hs-CRP and cardiovascular diseases. This study explored the association between hs-CRP and cancer, using a large database of Korean health examination records. METHODS A total of 80,781 Koreans who visited the health pro...

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A cross-sectional study on serum high-sensitivity C-reactive protein level and shift work among reproductive age women

Background: Among the inflammatory factors, high-sensitivity C-reactive protein (hs-CRP) is one of the strongest predictors of cardiovascular disease. This study aimed to evaluate the relationship of serum hs-CRP level with shift work among reproductive age women. Methods: This cross-sectional study was conducted from September 2017 to May 2018 in three cities in Mazandaran Province, North of ...

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ژورنال

عنوان ژورنال: Clinical Chemistry

سال: 2001

ISSN: 0009-9147,1530-8561

DOI: 10.1093/clinchem/47.9.1743a